Microcircuits Special Feature Microcircuits in action – from CPGs to neocortex
نویسندگان
چکیده
Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, S-17177 Stockholm, Sweden Laboratory for Neural Microcircuitry, Brain Mind Institute, EPFL, Lausanne CH-1015, Switzerland Laboratory of Theoretical Neurobiology, Institute Born-Bunge, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium School of Neurology, Neurobiology and Psychiatry, University of Newcastle-upon-Tyne, Newcastle-upon-Tyne, NE2 4HH, UK
منابع مشابه
Dendritic Excitability and Gain Control in Recurrent Cortical Microcircuits
Layer 5 thick tufted pyramidal cells (TTCs) in the neocortex are particularly electrically complex, owing to their highly excitable dendrites. The interplay between dendritic nonlinearities and recurrent cortical microcircuit activity in shaping network response is largely unknown. We simulated detailed conductance-based models of TTCs forming recurrent microcircuits that were interconnected as...
متن کاملSynaptic pathways in neural microcircuits.
The functions performed by different neural microcircuits depend on the anatomical and physiological properties of the various synaptic pathways connecting neurons. Neural microcircuits across various species and brain regions are similar in terms of their repertoire of neurotransmitters, their synaptic kinetics, their short-term and long-term plasticity, and the target-specificity of their syn...
متن کاملMicrocircuits Special Feature Biophysically detailed modelling of microcircuits and beyond
* In this TINS special feature, the term ‘microcircuit’ is used to denote a minimal Realistic bottom-up modelling has been seminal to understanding which properties of microcircuits control their dynamic behaviour, such as the locomotor rhythms generated by central pattern generators. In this article of the TINSMicrocircuits Special Feature, we review recent modelling work on the leech-heartbea...
متن کاملStereotyped position of local synaptic targets in neocortex.
The microcircuitry of the mammalian neocortex remains largely unknown. Although the neocortex could be composed of scores of precise circuits, an alternative possibility is that local connectivity is probabilistic or even random. To examine the precision and degree of determinism in the neocortical microcircuitry, we used optical probing to reconstruct microcircuits in layer 5 from mouse primar...
متن کاملInter-laminar microcircuits across neocortex: repair and augmentation
INTRODUCTION Repair and brain augmentation approaches, such as brain-machine interfaces, neural stimulation and other neural prostheses, have experienced a rapid development during the last decade (Nicolelis et al., 2003; Lebedev and Nicolelis, 2006). Still, only few of these methods target the fine microcircuitry of the brain (Jones and Rakic, 2010; Opris et al., 2012a). Here, it is highlighte...
متن کامل